Extrinsic and intrinsic pathways to caspase-3 activation



This photo was viewed 1 times and was downloaded in full size 0 times.

This photo was liked 0 times

Source page:


?esky: Vnit?ní a vn?jší cesty aktivace kaspázy 3: DISC (death-inducing signaling complex), MAC (mitochondrial apoptosis-induced channel) a apoptosom
English: Figure 1. Extrinsic and intrinsic pathways to caspase-3 activation. Overview of pathways to caspase-3 activation. Each separate gray region represent the three modules: DISC (death-inducing signaling complex), MAC (mitochondrial apoptosis-induced channel) and apoptosome. Species and their symbols are: FasL (FasL), FasR (FasR), DISC (DISC), procaspase-8 and caspase-8 (Casp8), bifunctional apoptosis inhibitor (BAR), procaspase-3 and caspase-3 (Casp3), XIAP (XIAP), Bid and truncated Bid (Bid), Bax (Bax), tBid - Bax2 complex (tBid - Bax2), Smac (Smac), Apaf-1 (Apaf), cytochrome c (Cytc), apoptosome (Apop), procaspase-9 and caspase-9 (Casp9). Arrows denote chemical conversions or catalyzed reactions while hammerheads represent inhibition.
Date 2008(2008)
Source Construction and analysis of a modular model of caspase activation in apoptosis
Author Harrington HA, Ho KL, Ghosh S, Tung KC
(Reusing this file)

© 2008 Harrington et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

w:en:Creative Commons
This file is licensed under the Creative Commons Attribution 2.5 Generic license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must attribute the work in the manner specified by the author or licensor (but not in any way that suggests that they endorse you or your use of the work).

Only registered users can post comments. Please login.

EXIF data:
File name extrinsic_and_intrinsic_pathways_to_caspase-3_activation.jpg
Size, Mbytes 0.08866015625
Mime type image/jpeg

See some ads as well as other free photos:

The images at Free-Photos.biz come mainly from Wikimedia Commons or from our own production. The photos are either in the public domain, or licensed under free linceses: Free-Photos.biz license, GPL, Creative Commons or Free-Art license. Some very few other photos where uploaded to Free-Photos.biz by our users and released into the public domain or into free usage under another free license (like GPL etc.)

While the copyright and licensing information supplied for each photo is believed to be accurate, Free-Photos.biz does not provide any warranty regarding the copyright status or correctness of licensing terms. If you decide to reuse the images from Free-Photos.biz, you should verify the copyright status of each image just as you would when obtaining images from other sources.

The use of depictions of living or deceased persons may be restricted in some jurisdictions by laws regarding personality rights. Such images are exhibited at Free-Photos.biz as works of art that serve higher artistic interests.

christianity portal